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Sunday, March 16, 2008

Healthy Gums May Prevent Systemic Diseases

Recent research shows that diabetes, low birth weight babies and heart disease are linked to gum and bone disease in the mouth that can be prevented by teeth cleanings. Treating gum disease might even prevent heart attacks, a new study suggests.

"Certain bacteria present in the mouth may be related to clogging up the arteries by contributing to the plaque that builds on the walls of the arteries," said New York University oral microbiologist Walter Bretz.

And treating gum disease, or periodontal disease, can improve the long-term function of endothelial cells that line blood vessel walls, according to a study conducted by researchers at the University of Connecticut Health Center. With better performing endothelial cells, plaques that cause heart disease will decrease, diminishing the risk of triggering a heart attack. The authors of the study, detailed in the March 1 issue of the New England Journal of Medicine, estimate that severe periodontitis affects up to 1 percent of adults in the U.S., and as many as 80 percent of American adults have some form of periodontal disease.

Periodontal disease is also quite common among pregnant women. Expectant mothers' gums react differently to the bacteria due to their increased levels of estrogen and progesterone. Women may experience swelling, bleeding or tenderness in the gum tissue. Several studies have linked gum disease to an increased risk of giving birth to a premature and underweight baby. Yet, an article published in a 2006 issue of the New England Journal of Medicine reported that, although treatment of gum disease in pregnant women is safe and improves periodontal health, preterm birth and low birth-weight babies were unaffected by the treatment.

The jury is still out on whether a mother's unhealthy gums can affect her unborn baby, but scientists are learning more from a large clinical trial currently under way at the University of Minnesota, focusing on whether treating periodontal diseases in pregnant women may prevent preterm and low birth-weight babies.

Unlike the case for pregnancy, researchers have found direct links between gum disease and diabetes. Gum disease is known to increase the risk of diabetes, and vice versa. Studies show that inflammatory periodontal diseases may increase insulin in the same way that obesity increases insulin. Meanwhile, doctors recognize diabetes as an important risk factor for severe gum disease and infection that may result in the destruction of tissues and bone surrounding the tooth.

Taking care of teeth can combat complications of diabetes and may reduce inflammation throughout the body associated with diseases such as cardiovascular disease.

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